Varicella Zoster - Chickenpox Immunity Blood Test
VARICELLA ZOSTER - CHICKENPOX IMMUNITY BLOOD TEST
Varicella Zoster, also referred to as the virus responsible for chickenpox and shingles, is a type of herpes virus. In its abbreviated form it is referred to as VZV, this is how it appears on a lot of request forms.
The Varicella Zoster virus (sometimes just caused VZV) is the virus that is responsible for chicken pox and shingles. The majority of people in the UK will be infected with VZV at some point in childhood and this will confer immunity to them. The virus can then lay dormant in the bodyâs nervous system and may reactivate later in life as the painful, blistering rash known as shingles.
When someone is initially infected with VZV, the body mounts an immune response which includes the production of the immunoglobulin IgM. A few weeks later, the body produces the immunoglobulin IgG which persists in the blood as part of the immune systemâs âmemoryâ of the virus, whilst IgM levels fall.
A positive IgG and a negative IgM therefore demonstrates previous infection (or vaccination) and the presence of immunity.
1 BIOMARKER
-
Varicella Zoster, Chicken Pox
- Varicella Zoster IgG (Immunity and past infection)
REPORTING OF LEVELS
The levels are reported as POSITIVE, EQUIVOCAL or NEGATIVE.Â
POSITIVE: > 150 = IMMUNE. No upper limit. Antibodies present against the pathogen. There has been contact with the antigen (pathogen resp. vaccine).
NEGATIVE: The sample contains no antibodies against the pathogen. A previous contact with the antigen (pathogen resp. vaccine) is unlikely.
EQUIVOCAL: Antibodies against the pathogen could not be detected clearly. You will have to repeat the test with a fresh sample in 2-4 weeks. If it is equivocal again, the sample is judged as negative.
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Description
VARICELLA ZOSTER - CHICKENPOX IMMUNITY BLOOD TEST
Varicella Zoster, also referred to as the virus responsible for chickenpox and shingles, is a type of herpes virus. In its abbreviated form it is referred to as VZV, this is how it appears on a lot of request forms.
The Varicella Zoster virus (sometimes just caused VZV) is the virus that is responsible for chicken pox and shingles. The majority of people in the UK will be infected with VZV at some point in childhood and this will confer immunity to them. The virus can then lay dormant in the bodyâs nervous system and may reactivate later in life as the painful, blistering rash known as shingles.
When someone is initially infected with VZV, the body mounts an immune response which includes the production of the immunoglobulin IgM. A few weeks later, the body produces the immunoglobulin IgG which persists in the blood as part of the immune systemâs âmemoryâ of the virus, whilst IgM levels fall.
A positive IgG and a negative IgM therefore demonstrates previous infection (or vaccination) and the presence of immunity.
1 BIOMARKER
-
Varicella Zoster, Chicken Pox
- Varicella Zoster IgG (Immunity and past infection)
REPORTING OF LEVELS
The levels are reported as POSITIVE, EQUIVOCAL or NEGATIVE.Â
POSITIVE: > 150 = IMMUNE. No upper limit. Antibodies present against the pathogen. There has been contact with the antigen (pathogen resp. vaccine).
NEGATIVE: The sample contains no antibodies against the pathogen. A previous contact with the antigen (pathogen resp. vaccine) is unlikely.
EQUIVOCAL: Antibodies against the pathogen could not be detected clearly. You will have to repeat the test with a fresh sample in 2-4 weeks. If it is equivocal again, the sample is judged as negative.
